Acid Hyaluronic also known as hyaluronan and hyaluronate, is glycosaminoglycan as chondroitin. Though from the same group, hyaluronan it is distinguished even among another glycosaminoglycans that it not sulfated and forms in a plasma membrane, not in Golgi. It can be also very big, with molecular weight which often reaches millions in value. It anionnoe, non-sulfated the substance is widely distributed everywhere on connecting, epitelial'nym and to nervous fabrics. It is one of the main components of extracellular liquids and promotes very fast increase in a cell and moving. Besides, hyaluronan can play also a role in a progression of a small amount of malicious tumours and as also find, an integral part of an extracellular capsule of group streptococcus which as believe, adds to it yadovitosti.
This obiquitous polymer of carbohydrates has been described as a molecule of "a sticky thing" to 1970. It is especially important component sinovial'noy liquids and as found, has increased the viscosity along with lubricin. It - also the important component of articulate cartilages also functions as a coat round everyone chondrocyte cells. When certain process is made, which involves fastening hyaluronan and aggrecan monomerov, the big and very is negative-charged set can be generated. The turning out substance imbibes water and is responsible for flexibility and resistance of cartilages. Approximately one third of total sum in a body is synthesised and worsens everyday and molecular weight in umen'sheniyakh a cartilage as advance payments of age, but its quantity, apparently, increases.
Hyaluronan also it is found in a skin where it plays an essential role of under repair damaged fabrics. However, certain factors as ULTRA-VIOLET beams of the sun increase norm of degradation of this structure. Besides, it also promotes fabric hydrodynamics, movement and fast increase in cells, along with its role during many interactions of a receptor of a surface of a cell. Its role in a progression of tumours can be explained its interaction with receptors CD44 which participate in interactions of sticking of the cell, necessary for tumour cells to extend. Also it is considered that this structure takes part during brain development.
For people with osteoporosis this structure can be very favourable in the sense that it can help yours sinovial'noy to a liquid to become more viscous again. Hence, increasing its ability to resist to compression and to minimise a pain you feel during movement and accompanying ignition and other signs and signs as stiffness, outpouring, tenderness, and t.p.
Process of increase in viscosity sinovial'noy liquids (among others) is viscosupplementation. Using this method, not only that sinovial'naya the liquid is increased from the point of view of viscosity, but it also reduces a pain, a tumour and ignition. It also increases articulate depth of a cartilage on the cargo having surfaces. It can be reached, doing one of these two methods, and they: a capture of oral additions and injection actual hyaluronan in the mentioned joint. Injection hyaluronic acid in the mentioned or gouty joint as showed researches, has improved incorporated health, increasing mobility of joints because of increased sinovial'nykh liquid levels, reducing prostaglandiny to reduce a pain, and increasing depth of a cartilage.
